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Glossary

Plain-language explanations of the tests, measures, therapies, and concepts used in longevity medicine.

A

Autophagy

Autophagy is a set of cellular processes that deliver selected components to lysosomes for breakdown and recycling.

B

Biological Age

Biological age is an umbrella term for estimates intended to summarize how age-associated features compare with a reference population.

Biomarker

A biomarker is a measurable biological characteristic used to describe a normal process, a health-related process, or a response to an exposure.

C

Cellular Senescence

Cellular senescence is a state in which a cell remains metabolically active but has entered a durable pause in division.

H

Hallmarks of Aging

The hallmarks of aging are a scientific framework that groups interconnected biological processes associated with changes observed during ageing.

Healthspan

Healthspan is the portion of a person's life spent with a desired level of health, function, and independence.

L

Longevity Medicine

Longevity medicine is an emerging clinical label for care organized around long-term health, function, risk assessment, and ageing-related change.

M

Mitochondrial Function

Mitochondrial function describes the activities of mitochondria in energy conversion, cellular signalling, metabolism, and regulation of cell survival.

P

Precision Medicine

Precision medicine is an approach that uses individual clinical, biological, environmental, and lifestyle information to refine healthcare decisions.

S

Sarcopenia

Sarcopenia is a clinical condition characterized by low muscle strength together with reduced muscle quantity or quality, often associated with ageing.